Searchable abstracts of presentations at key conferences in endocrinology

ea0031s3.3 | Nurture not nature: epigenetics and disease susceptibility | SFEBES2013

Epigenetic changes associated with prenatal exposure to famine in humans

Lumey L.H.

Epidemiologic studies suggest that adult disease risk may be associated with adverse environmental conditions early in development but the biological mechanisms behind these relations are unclear.Our group used the circumstances of the Dutch famine of 1944–1945 to evaluate epigenetic changes in men and women with prenatal famine exposure during the Second World War. Study subjects were followed from birth to age ∼58 years. To minimize potentia...